ORC suspends Casie Coleman indefinitely

[AmyHollar]

The rules need to be more realistic.

This may be the smartest thing you have EVER said. 

[AmyHollar]

It is just another black eye for the sport. Especially for outsiders looking in who don't understand it. Guilty until proven innocent.

  And it is where we have DROPPED the ball...........every positive is not a NARCOTIC PERFORMANCE ENHANCER.

To think Coleman is a genius and can drop horses three seconds for using flucord is as ridiculous as saying I can hoist full wheelbarrows over my head after I take four Ibuprofen.

[AmyHollar]

For the record.....Casie unfriended me long ago on Facebook..........and I was grateful..........her grammar had my butt puckering..........which leads me to wonder how in the hell anyone could think she is smart enough to outsmart every racing jurisdiction in North America...............or how about she's been damn lucky..............right place at the right time to build up a high quality stable.......to use top notch vets, caretakers, blacksmiths and feeding regimes..............I envy it.............you are never going to convince me there is a "magic drug"...........and if it is ever found.......I'm using it on my heel spur first.

[careless hal]

We need Lockjaw to put up a pick of a horse smoking a reefer with old LVGD driving.  Hell, at least the bettors would know what is going on!

[3 wide and wingin]

For the record.....Casie unfriended me long ago on Facebook..........and I was grateful..........her grammar had my butt puckering..........which leads me to wonder how in the hell anyone could think she is smart enough to outsmart every racing jurisdiction in North America...............or how about she's been damn lucky..............right place at the right time to build up a high quality stable.......to use top notch vets, caretakers, blacksmiths and feeding regimes..............I envy it.............you are never going to convince me there is a "magic drug"...........and if it is ever found.......I'm using it on my heel spur first.

Just so you know.
She unfriended me too.

Why?

Her house got broken into while she was on vacation.
Posting about how great it was.

She was one of the first FB people to post about vacations and get robbed.

When is your vacation?

I could use some long johns and kersene oil for my lamp.

[AmyHollar]

Kerosene?  Too fancy for us..........we just bed down over manure and hope it doesn't cool off till morning.

[The Skipper]

OK I am a dumb f#ck that knows nothing, so please help me ! How do hundreds or maybe thousands of

races go every week but only a couple people get cracked for this shit ? And I'm thinking this stuff is used

for other things other then diaper rash, but remember I am a dumb f#ck !
 


 Flucort Solution Caution
 
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
 
General
 
FLUCORT (flumethasone) is a chemical modification of prednisolone which possesses greater anti-inflammatory and gluconeogenic properties than the parent compound when compared on an equivalent basis. Due to the potency of FLUCORT Solution, dosage recommendations should be consulted prior to drug administration. Chemically, it is 6α, 9α-difluoro-16α methylprednisolone. The structural formula is as follows:
 

Description
 
The active ingredient of FLUCORT Solution is flumethasone which occurs as a white to creamy white, odorless, crystalline powder. The appearance of FLUCORT Solution is a clear colorless to slightly yellowish mobile liquid.
 
Each mL of the injectable preparation contains 0.5 mg flumethasone, 420 mg polyethylene glycol 400, 9 mg benzyl alcohol as a preservative, 8 mg sodium chloride, 0.1 mg citric acid, sodium hydroxide and/or hydrochloric acid for pH adjustment when necessary, and water for injection USP, q.s.
 
Clinical Pharmacology
 
Flumethasone has been reported (1) to possess 700 times the glucocorticoid activity of cortisol (hydrocortisone) as measured in the liver glycogen deposition assay in the rat; 120 times that of cortisol in the cotton pellet assay in the rat; and also in the same animal, shows a net excretion of sodium.
 
In similar tests in rats, another report (2) showed flumethasone 730 times more potent than cortisol in the granuloma inhibition assay and 165 times the activity of cortisol in the glycogen deposition assay. The same report showed that in man, the compound possessed 7.8 times the potency of prednisolone.
 
An additional report (3) indicated that flumethasone possessed 677 times the potency of cortisol in the liver glycogen deposition test in the rat, and 30, 25, and 31 times respectively, the eosinopenic, hyperglycemic and antirheumatic potency of cortisol, as measured in man.
 
Veterinary experimental studies utilizing the eosinophil depression test in normal dogs and blood glucose elevation and eosinophil depression in normal cattle as parameters of drug activity, in comparison tests involving prednisone and dexamethasone, indicate that flumethasone possesses greater anti-inflammatory and gluconeogenic activity than these compounds, on an equivalent basis.
 
Clinical evidence of drug potency obtained during evaluation of the compound and based upon effective drug dosage levels further substantiates the above experimental findings.
 
General Effects of Adrenocorticoids
 
The adrenocorticoids are divided into two main classes: mineralocorticoids and glucocorticoids, based on their major physiologic and pharmacologic actions.
 
Mineralocorticoids such as the naturally occurring desoxycorticosterone and aldosterone are mainly concerned with hydration, sodium and potassium regulation and the normal renal glomerular filtration of these two electrolytes. The mineralocorticoids have little if any effect as anti-inflammatory agents, and are not widely used in medicine.
 
Glucocorticoids include the naturally occurring compounds, cortisone and hydrocortisone. Their major effects are as follows:
 
1. Increase protein catabolism and gluconeogenesis.
 
2. Depression of lymphoid tissue, fibroblasts and eosinophils.
 
3. Increase the sense of well being and tolerance to pain.
 
4. Depress thyroid function and anterior pituitary function through reciprocal influences.
 
5. Influence vasoconstrictive response of the circulatory system to norepinephrine, helping to maintain blood pressure.
 
6. Increase renal flow.
 
7. Influence gastric HCl and pepsin production.
 
8. Reduces the secretion of mucus from respiratory and enteric mucosa.
 
9. Affect to some degree sodium retention and potassium excretion.
 
10. Stimulate erythropoiesis and myelopoiesis.
 
Synthetic analogues of cortisone and hydrocortisone containing a double bond between carbon 1 and 2 of the corticosteroid nucleus, resulted in compounds with a greatly decreased effect on electrolyte metabolism. Additional molecular changes present in other synthetic corticoids presently used in medicine such as methylation at carbons 6 or 16 and hydroxylation at carbon 16, have led to a further decrease in electrolyte imbalance noted with the naturally occurring glucocorticoids. Fluorination at carbon 6 and/or 9 have led to a marked increase in anti-inflammatory activity.
 
The synthetic glucocorticoids exhibit a marked increase in potency in that a smaller amount of drug is required to elicit the same effects seen only with larger amounts of the natural glucocorticoids. It is also noted that the synthetic analogues persist for a longer period of time in the body which is believed due to their slower metabolism and excretion.
 
Flucort Solution Indications

FLUCORT (flumethasone) Solution is recommended for the various rheumatic, allergic, dermatologic and other disease states which are known to be responsive to the anti-inflammatory corticoids.
 
Equine Indications
 
1. Musculoskeletal conditions due to inflammation, where permanent structural changes do not exist, such as bursitis, carpitis, osselets and myositis. Following therapy an appropriate period of rest should be instituted to allow a more normal return to function of the affected part.
 
2. In allergic states such as hives, urticaria and insect bites.
 
Canine Indications
 
1. Musculoskeletal conditions due to inflammation of muscles or joints and accessory structures, where permanent structural changes do not exist, such as arthritis, osteoarthritis, the disc syndrome and myositis. In septic arthritis appropriate antibacterial therapy should be concurrently administered.
 
2. In certain acute and chronic dermatoses of varying etiology to help control the pruritus, irritation and inflammation associated with these conditions. The drug has proven useful in otitis externa in conjunction with topical medication for similar reasons.
 
3. In allergic states such as hives, urticaria and insect bites.
 
4. Shock and shock-like states, (4) by intravenous administration.
 
Feline Indications
 
1. In certain acute and chronic dermatoses of varying etiology to help control the pruritus, irritation and inflammation associated with these conditions.

[The Skipper]

Wow  ...  Increase the sense of well being and tolerance to pain...wonder if that would help any horses run

 faster ? Reduces the secretion of mucus from respiratory and enteric mucosa....That probably wouldn't

help much either right ? Please help the dumb f#ck here cause i don't understand this is so confusing

to an idiot like myself.

[pezz97]

This is 2 suspensions in a year for her in Canada! She got 45 days for a positive on Reibercrombie last March

[Jeremy]

Wow  ...  Increase the sense of well being and tolerance to pain...wonder if that would help any horses run

 faster ? Reduces the secretion of mucus from respiratory and enteric mucosa....That probably wouldn't

help much either right ? Please help the dumb f#ck here cause i don't understand this is so confusing

to an idiot like myself.

Sounds like I need to be taking this stuff

[sea biscuit]

Flumethasone? She got suspended indefinitely for rubbing stuff on their legs? You have got to be kidding me.

The three horses who got the post race positive were at Woodbine while she was in Florida vacationing.

By the way none of the three horses won their respective races not that it matters.

Her hearing is scheduled for Mar 11

[careless hal]

I'm taking 5 years off to go back to school and become a pharmacist.  Then I can return and take up my capping chores again.

[The Skipper]

I'm taking 5 years off to go back to school and become a pharmacist.  Then I can return and take up my capping chores again.

Hal, you already know it's often not the best trainer, it's the best chemist ! At the big purse tracks MOSTLY.

To make it simple lets just say my buddy Ralph takes 1 ambien a night to sleep with and that is with a

perscription and therapeutic to him and legal, now my buddy Herman stays up for 2 days and then takes

5 ambien and gets him screwier then Dennis Rodman on a 6 day bender. Anyway that's the way a dumb

f#ck like me looks at it. 

[The Skipper]

Sounds like I need to be taking this stuff

You and me both buddy, I could really use it on weds night bowling, if I did I might break my streak

of bowling under 450 once.  Oh I forgot I don't have diaper rash (yet) 

[Just Saying]

Skipper: Before reading the pharmocology report I never knew there were that many big words. I'd have worn out 3 dictionaries looking them up. That's why I studied mechanical engineering. I learned complicated stuff like 80,000 lbs of down-pressure on a certain weld will make the f#cking thing break.

Don't even get me started on rocket surgery.